| Eastern Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 17 | 39 | 33:12 | 21 | 12 | 3 | 2 |
| 2. | Inter Miami CF | 17 | 37 | 43:30 | 13 | 11 | 4 | 2 |
| 3. | New England Revolution | 16 | 29 | 26:19 | 7 | 9 | 2 | 5 |
| 4. | Chicago Fire | 16 | 26 | 30:22 | 8 | 8 | 2 | 6 |
| 5. | New York City FC | 17 | 25 | 30:23 | 7 | 7 | 4 | 6 |
| 6. | Charlotte FC | 17 | 25 | 28:25 | 3 | 7 | 4 | 6 |
| 7. | Cincinnati FC | 17 | 23 | 41:42 | -1 | 6 | 5 | 6 |
| 8. | D.C. United | 17 | 22 | 24:27 | -3 | 5 | 7 | 5 |
| 9. | New York Red Bulls | 17 | 22 | 26:37 | -11 | 6 | 4 | 7 |
| 10. | Orlando City | 17 | 20 | 28:44 | -16 | 6 | 2 | 9 |
| 11. | Columbus Crew | 17 | 19 | 24:26 | -2 | 5 | 4 | 8 |
| 12. | Toronto FC | 17 | 16 | 23:31 | -8 | 3 | 7 | 7 |
| 13. | CF Montreal | 17 | 15 | 22:33 | -11 | 4 | 3 | 10 |
| 14. | Philadelphia Union | 17 | 13 | 22:31 | -9 | 3 | 4 | 10 |
| 15. | Atlanta United FC | 17 | 12 | 17:30 | -13 | 3 | 3 | 11 |
| Western Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 16 | 33 | 37:16 | 21 | 10 | 3 | 3 |
| 2. | Los Angeles FC | 18 | 33 | 34:18 | 16 | 10 | 3 | 5 |
| 3. | San Jose Earthquakes | 17 | 33 | 35:20 | 15 | 10 | 3 | 4 |
| 4. | FC Dallas | 17 | 26 | 32:25 | 7 | 7 | 5 | 5 |
| 5. | Real Salt Lake | 16 | 26 | 28:24 | 4 | 8 | 2 | 6 |
| 6. | Houston Dynamo | 16 | 26 | 23:24 | -1 | 8 | 2 | 6 |
| 7. | St. Louis City SC | 17 | 25 | 23:23 | 0 | 7 | 4 | 6 |
| 8. | Seattle Sounders | 16 | 24 | 19:20 | -1 | 7 | 3 | 6 |
| 9. | Minnesota United FC | 17 | 23 | 19:24 | -5 | 6 | 5 | 6 |
| 10. | Portland Timbers | 17 | 21 | 31:32 | -1 | 6 | 3 | 8 |
| 11. | Los Angeles Galaxy | 18 | 21 | 24:29 | -5 | 5 | 6 | 7 |
| 12. | San Diego FC | 17 | 20 | 31:28 | 3 | 5 | 5 | 7 |
| 13. | Colorado Rapids | 17 | 19 | 26:25 | 1 | 6 | 1 | 10 |
| 14. | Austin FC | 17 | 17 | 22:35 | -13 | 4 | 5 | 8 |
| 15. | Sporting Kansas City | 17 | 14 | 18:44 | -26 | 4 | 2 | 11 |